Endocrine Abstracts

Background: This study was designed to investigate prorenin and secreted frizzled-related protein-4 (SFRP-4) levels in pregnancies with or without gestational diabetes mellitus (GDM).Materials and methods: A total of 76 pregnant women were included in the study. Thirty-five of the pregnant women were included in the GDM group according to the results of oral glucose tolerance tests (OGTT) and 41 pregnant women were included in the control group.<p cl...

Introduction: Primary hyperparathyroidism (PHPT) is a disease that is characterized by elevated calcium and parathyroid hormone levels. The most common cause of PHPT is the paratiroid adenoma and the first line treatment option is surgical removal of the adenoma. Rarely, the haemorrhage in the lesion may cause the spontaneous remission of the disease.Case report: A 54-year-old woman patient with fatigue was referred to our department due to calcium level...

Introduction: SFRP-4 is a recently described inflammatory cytokine influencing insulin secretion from human β cells as an extracellular modulator of Wingless (Wnt) pathway. The aim of this study is to compare serum SFRP-4 levels in patients with normal glucose tolerance (NGT), impaired glucose tolerance (IGT) and type 2 diabetes (T2DM), and to investigate its relation with other parameters.Methods: The study included 152 patients who applied to the ...

Introduction: Struma ovarii is an uncommon ovarian neoplasm that more than half of itself is made up of thyroid tissue. In clinical trials about the disease, malign transformation has been detected at the rate of 0.5–5%. Because of the disease’s rareness, there is no absolute agreement about diagnosis and treatment of the disease.Case report: A 33-year-old woman admitted to gynecology department with abdominal pain. Her pelvic MR revealed 147&#...

Introduction: Current studies suggest that fractalkine (FKN) could be a pathogenic factor associated with adipocyte dysfunction and type 2 diabetes (T2DM) and have shown that FKN serum levels are increased in T2DM patients. The aim of this study was determined as evaluating the change of FKN levels that will occur with oral glucose tolerance test (OGTT).Methods: The study included 67 patients to whom OGTT was applied. The patients with the history of dia...

Introduction: There are serological findings and mucosal injury similar to the classical form but no gastrointestinal symptoms in subclinical Celiac disease (CD). In this article, we present a case of subclinical CD presented with postpartum low-back pain, in whom we discovered severe lumbar vertebral osteoporosis.Case report: A 35-year-old woman admitted to our outpatient clinic with severe low-back pain. The patient had given birth 5 months ag...

Introduction: There is some evidence that a rise in the androgen hormone levels increases the risk for the development of a cardiovascular disease, obtained from the studies conducted on women with polycystic ovary and on men with androgenic alopecia. Inflammatory substances tend to increase in polycystic ovary syndrome and in androgenic alopecia. On this basis, we conducted a study that aimed to evaluate the early cardiovascular and metabolic effects in male patients with and...

Androgenic alopecia (AGA) is an important clinical issue that can cause significant cosmetic problems. Many factors such as genetic, androgen hormones, environmental factors, and inflammation are involved in the pathogenesis of androgenic alopecia. Insulin and insulin resistance have been found increased in individuals with AGA. There are many proinflammatory substances which are playing role in the pathogenesis of androgenic alopecia. Secreted frizzled related protein-4 (SFRP...

Background: Netrin-1 is an early biomarker of acute kidney injury. Besides, recent studies have showed that netrin-1 promotes angiogenesis; but its usefulness for peripheral artery disease (PAD) in type 2 diabetes patients is unknown.This study aimed at investigating whether netrin-1 levelsare increased in peripheral artery disease among patients with type 2 diabetes and also investigating possible associationsbetween diabetic nephropathy (DN) and PAD.Ma...

Aim: Thirty female Wistar albino rats with surgically endometriotic implants were randomly randomized into three treatment groups: oral rosuvastatin (20 mg kg per day; oral rosuvastatin group 1; n=10), oral progesterone (Dienogest group 2; n=10), and intraperitoneal bevacizumab (2.5 mg/kg of single intaperitoneal injection of bevacizumab; group 3; n=10) respectively, for 10 day and post-treatment variables were compared.Results...